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The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak house?
There is considerable evidence that the potent vasoconstrictor endothelin-1 (ET-1) contributes to the pathogenesis of a variety of cardiovascular diseases. As such, pharmacological manipulation of the ET system might represent a promising therapeutic goal. Many clinical trials have assessed the pote...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275436/ https://ncbi.nlm.nih.gov/pubmed/17965745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707516 |
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