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Disease sequence from mutant rhodopsin allele to rod and cone photoreceptor degeneration in man

Mutations in the gene encoding rhodopsin, the visual pigment in rod photoreceptors, lead to retinal degeneration in species from Drosophila to man. The pathogenic sequence from rod cell-specific mutation to degeneration of rods and cones remains unclear. To understand the disease process in man, we...

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Detalhes bibliográficos
Main Authors: Cideciyan, Artur V., Hood, Donald C., Huang, Yijun, Banin, Eyal, Li, Zong-Yi, Stone, Edwin M., Milam, Ann H., Jacobson, Samuel G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22754/
https://ncbi.nlm.nih.gov/pubmed/9618546
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