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Effect of ionic strength and presence of serum on lipoplexes structure monitorized by FRET

BACKGROUND: Serum and high ionic strength solutions constitute important barriers to cationic lipid-mediated intravenous gene transfer. Preparation or incubation of lipoplexes in these media results in alteration of their biophysical properties, generally leading to a decrease in transfection effici...

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Detalhes bibliográficos
Main Authors: Madeira, Catarina, Loura, Luís MS, Prieto, Manuel, Fedorov, Aleksander, Aires-Barros, M Raquel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275333/
https://ncbi.nlm.nih.gov/pubmed/18302788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-8-20
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