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Supervised Lowess normalization of comparative genome hybridization data – application to lactococcal strain comparisons

BACKGROUND: Array-based comparative genome hybridization (aCGH) is commonly used to determine the genomic content of bacterial strains. Since prokaryotes in general have less conserved genome sequences than eukaryotes, sequence divergences between the genes in the genomes used for an aCGH experiment...

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Main Authors: van Hijum, Sacha AFT, Baerends, Richard JS, Zomer, Aldert L, Karsens, Harma A, Martin-Requena, Victoria, Trelles, Oswaldo, Kok, Jan, Kuipers, Oscar P
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275246/
https://ncbi.nlm.nih.gov/pubmed/18267014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-93
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