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PITX2 gain-of-function induced defects in mouse forelimb development

BACKGROUND: Limb development and patterning originate from a complex interplay between the skeletal elements, tendons, and muscles of the limb. One of the genes involved in patterning of limb muscles is the homeobox transcription factor Pitx2 but its role in forelimb development is uncharacterized....

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Detalhes bibliográficos
Main Authors: Holmberg, Johan, Ingner, Gorel, Johansson, Curt, Leander, Peter, Hjalt, Tord A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275225/
https://ncbi.nlm.nih.gov/pubmed/18312615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-8-25
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