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Overexpression of E2F5/p130, but not E2F5 alone, can inhibit E2F-induced cell cycle entry in transgenic mice

PURPOSE: The retinoblastoma (Rb) gene family member p130 binds preferentially to the E2F5 transcription factor and forms a repressive E2F5/p130 complex that inhibits cell cycle progression and tumor growth. It is unclear whether E2F5, either alone or in combination with p130, can interfere with the...

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Main Authors: Chen, Qin, Liang, Dongcai, Overbeek, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Vision 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275213/
https://ncbi.nlm.nih.gov/pubmed/18385796
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