Erythrocyte aldose reductase activity and sorbitol levels in diabetic retinopathy

PURPOSE: Activation of polyol pathway due to increased aldose reductase (ALR2) activity has been implicated in the development of diabetic complications including diabetic retinopathy (DR), a leading cause of blindness. However, the relationship between hyperglycemia-induced activation of polyol pat...

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Main Authors: Reddy, G. Bhanuprakash, Satyanarayana, A., Balakrishna, N., Ayyagari, Radha, Padma, M., Viswanath, K., Petrash, J. Mark
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275210/
https://ncbi.nlm.nih.gov/pubmed/18385795
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