Interaction of p21(CDKN1A) with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair

The cell-cycle inhibitor p21(CDKN1A) has been suggested to directly participate in DNA repair, thanks to the interaction with PCNA. Yet, its role has remained unclear. Among proteins interacting with both p21 and PCNA, the histone acetyltransferase (HAT) p300 has been shown to participate in DNA rep...

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Main Authors: Cazzalini, Ornella, Perucca, Paola, Savio, Monica, Necchi, Daniela, Bianchi, Livia, Stivala, Lucia A., Ducommun, Bernard, Scovassi, A. Ivana, Prosperi, Ennio
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
Teme:
Molecular Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275133/
https://ncbi.nlm.nih.gov/pubmed/18263614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn014
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