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Increased numbers of circulating hematopoietic stem/progenitor cells are chronically maintained in patients treated with the CD49d blocking antibody natalizumab

Blockade of CD49d-mediated lymphocyte trafficking has been used therapeutically for certain autoimmune diseases, such as multiple sclerosis (MS). In addition to negative effects on the trafficking of mature lymphocytes to sites of inflammation, CD49d blockade in mice and monkeys rapidly mobilizes he...

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Sonraí Bibleagrafaíochta
Main Authors: Bonig, Halvard, Wundes, Annette, Chang, Kai-Hsin, Lucas, Sylvia, Papayannopoulou, Thalia
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275012/
https://ncbi.nlm.nih.gov/pubmed/18195093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-112052
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