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Human immunodeficiency virus evolution towards reduced replicative fitness in vivo and the development of AIDS
Human immunodeficiency virus (HIV) infection progresses to AIDS following an asymptomatic period during which the virus is thought to evolve towards increased fitness and pathogenicity. We show mathematically that progression to the strongest HIV-induced pathology requires evolution of the virus tow...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Royal Society
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2274968/ https://ncbi.nlm.nih.gov/pubmed/17666377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2007.0413 |
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