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Blockade of NMDA receptors prevents analgesic tolerance to repeated transcutaneous electrical nerve stimulation (TENS) in rats

Repeated daily application transcutaneous electrical nerve stimulation (TENS) results in tolerance, at spinal opioid receptors, to the anti-hyperalgesia produced by TENS. Since N-Methyl-D-Aspartate (NMDA) receptor antagonists prevent analgesic tolerance to opioid agonists we hypothesized that blocka...

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Detalhes bibliográficos
Main Authors: Hingne, Priyanka M., Sluka, Kathleen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2274833/
https://ncbi.nlm.nih.gov/pubmed/18061543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2007.10.010
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