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Absence of cytokine receptor-dependent specificity in red blood cell differentiation in vivo

Erythropoietin (EPO) is required for red blood cell development, but whether EPO-specific signals directly instruct erythroid differentiation is unknown. We used a dominant system in which constitutively active variants of the EPO receptor were introduced into erythroid progenitors in mice. Chimeric...

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Detalhes bibliográficos
Main Authors: Goldsmith, Mark A., Mikami, Aki, You, Yun, Liu, Kathleen D., Thomas, Liza, Pharr, Pamela, Longmore, Gregory D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22719/
https://ncbi.nlm.nih.gov/pubmed/9618529
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