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Structural and thermodynamic effects of ANS binding to human interleukin-1 receptor antagonist

Although 8-anilinonaphthalene-1-sulfonic acid (ANS) is frequently used in protein folding studies, the structural and thermodynamic effects of its binding to proteins are not well understood. Using high-resolution two-dimensional NMR and human interleukin-1 receptor antagonist (IL-1ra) as a model pr...

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Detalhes bibliográficos
Main Authors: Latypov, Ramil F., Liu, Dingjiang, Gunasekaran, Kannan, Harvey, Timothy S., Razinkov, Vladimir I., Raibekas, Andrei A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271160/
https://ncbi.nlm.nih.gov/pubmed/18305195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073332408
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