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Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20
Toll-like receptors (TLRs) on host cells are chronically engaged by microbial ligands during homeostatic conditions. These signals do not cause inflammatory immune responses in unperturbed mice, even though they drive innate and adaptive immune responses when combating microbial infections. A20 is a...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2271029/ https://ncbi.nlm.nih.gov/pubmed/18268035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071108 |
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