Maternal TLR4 and NOD2 Gene Variants, Pro-Inflammatory Phenotype and Susceptibility to Early-Onset Preeclampsia and HELLP Syndrome

BACKGROUND: Altered maternal inflammatory responses play a role in the development of preeclampsia and the hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome. We examined whether allelic variants of the innate immune receptors Toll-like receptor 4 (TLR4) and nucleotide-binding olig...

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Detalhes bibliográficos
Main Authors: van Rijn, Bas B., Franx, Arie, Steegers, Eric A. P., de Groot, Christianne J. M., Bertina, Rogier M., Pasterkamp, Gerard, Voorbij, Hieronymus A. M., Bruinse, Hein W., Roest, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270909/
https://ncbi.nlm.nih.gov/pubmed/18382655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001865
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