Homozygous carnitine palmitoyltransferase 1b (muscle isoform) deficiency is lethal in the mouse

Carnitine palmitoyltransferase-1 (CPT-1) catalyzes the rate-limiting step of mitochondrial β-oxidation of long chain fatty acids (LCFA), the most abundant fatty acids in mammalian membranes and in energy metabolism. Human deficiency of the muscle isoform CPT-1b is poorly understood. In the current s...

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Main Authors: Ji, Shaonin, You, Yun, Kerner, Janos, Hoppel, Charles L., Schoeb, Trenton R., Chick, Wallace S.H., Hamm, Doug A., Sharer, J. Daniel, Wood, Philip A.
Format: Artigo
Jezik:Inglês
Izdano: 2007
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270477/
https://ncbi.nlm.nih.gov/pubmed/18023382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2007.10.006
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