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Homozygous carnitine palmitoyltransferase 1b (muscle isoform) deficiency is lethal in the mouse
Carnitine palmitoyltransferase-1 (CPT-1) catalyzes the rate-limiting step of mitochondrial β-oxidation of long chain fatty acids (LCFA), the most abundant fatty acids in mammalian membranes and in energy metabolism. Human deficiency of the muscle isoform CPT-1b is poorly understood. In the current s...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2270477/ https://ncbi.nlm.nih.gov/pubmed/18023382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2007.10.006 |
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