REGULATED PROTEOLYTIC PROCESSING OF TIE1 MODULATES LIGAND RESPONSIVENESS OF THE RECEPTOR TYROSINE KINASE TIE2

Regulated ectodomain shedding followed by intramembrane proteolysis has recently been recognized as important in cell signaling and for degradation of several type I transmembrane proteins. The receptor tyrosine kinase Tie1 is known to undergo ectodomain cleavage generating a membrane tethered endod...

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Detalhes bibliográficos
Main Authors: Marron, Marie B, Singh, Harprit, Tahir, Tariq A, Kavumkal, Jais, Kim, Hak-Zoo, Koh, Gou Young, Brindle, Nicholas PJ
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270410/
https://ncbi.nlm.nih.gov/pubmed/17728252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M702535200
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