Protein kinase C-dependent modulation of Na(+) currents increases the excitability of rat neocortical pyramidal neurones

1. The effect of the protein kinase C (PKC) activator 1-oleoyl-2-acetyl-sn-glycerol (OAG) on TTX-sensitive Na(+) currents in neocortical pyramidal neurones was evaluated using voltage-clamp and intracellular current-clamp recordings. 2. In pyramid-shaped dissociated neurones, the addition of OAG to...

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Detalhes bibliográficos
Main Authors: Franceschetti, S, Taverna, S, Sancini, G, Panzica, F, Lombardi, R, Avanzini, G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270127/
https://ncbi.nlm.nih.gov/pubmed/11034619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.00291.x
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