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Zn(2+) current is mediated by voltage-gated Ca(2+) channels and enhanced by extracellular acidity in mouse cortical neurones

1. Mammalian neuronal voltage-gated Ca(2+) channels have been implicated as potential mediators of membrane permeability to Zn(2+). We tested directly whether voltage-gated Ca(2+) channels can flux Zn(2+) in whole-cell voltage-clamp recordings from cultured murine cortical neurones. 2. In the presen...

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Detalles Bibliográficos
Main Authors: Kerchner, Geoffrey A, Canzoniero, Lorella M T, Yu, Shan Ping, Ling, Cliff, Choi, Dennis W
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270119/
https://ncbi.nlm.nih.gov/pubmed/11018104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.00039.x
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