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Store depletion and store-operated Ca(2+) current in human prostate cancer LNCaP cells: involvement in apoptosis

1. In the present study, we investigated the mechanisms involved in the induction of apoptosis by the Ca(2+)-ATPase inhibitor thapsigargin (TG), in androgen-sensitive human prostate cancer LNCaP cells. 2. Exposure of fura-2-loaded LNCaP cells to TG in the presence of extracellular calcium produced a...

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Detalhes bibliográficos
Main Authors: Skryma, Roman, Mariot, Pascal, Le Bourhis, Xuefen, Van Coppenolle, Fabien, Shuba, Yaroslav, Abeele, Fabien Vanden, Legrand, Guillaume, Humez, Sandrine, Boilly, Benoni, Prevarskaya, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270062/
https://ncbi.nlm.nih.gov/pubmed/10944171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.00071.x
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