Cloning and expression of a FMRFamide-gated Na(+) channel from Helisoma trivolvis and comparison with the native neuronal channel

1. We have cloned a cDNA encoding a Phe-Met-Arg-Phe-NH(2) (FMRFamide)-gated Na(+) channel from nervous tissue of the pond snail Helisoma trivolvis (HtFaNaC) and expressed the channel in Xenopus oocytes. The deduced amino acid sequence of the protein expressed by HtFaNaC is 65 % identical to that of...

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Main Authors: Jeziorski, Michael C, Green, Kevin A, Sommerville, John, Cottrell, Glen A
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2000
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269999/
https://ncbi.nlm.nih.gov/pubmed/10878095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.00013.x
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