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Gentamicin blocks ACh-evoked K(+) current in guinea-pig outer hair cells by impairing Ca(2+) entry at the cholinergic receptor

1. Aminoglycoside antibiotics such as gentamicin are known to block the medial olivocochlear efferent system. In order to determine whether this inhibition takes place at the postsynaptic cholinergic receptors in outer hair cells (OHCs), we studied the effects of these polycationic molecules on chol...

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Detalhes bibliográficos
Main Authors: Blanchet, Christophe, Eróstegui, Carlos, Sugasawa, Masashi, Dulon, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269963/
https://ncbi.nlm.nih.gov/pubmed/10856118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.t01-1-00641.x
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