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Regulation of volume-activated chloride channels by P-glycoprotein: phosphorylation has the final say!
1. P-glycoprotein (Pgp) is a transmembrane transporter causing efflux of a number of chemically unrelated drugs and is responsible for resistance to a variety of anticancer drugs during chemotherapy. 2. Pgp overexpression in cells is also associated with volume-activated chloride channel activity; P...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2269906/ https://ncbi.nlm.nih.gov/pubmed/10790147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.00629.x |
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