Activation of the cAMP–protein kinase A pathway facilitates Na(+) translocation by the Na(+)–K(+) pump in guinea-pig ventricular myocytes

1. The effects of the adenylyl cyclase activator forskolin on steady-state and transient currents generated by the Na(+)-K(+) pump were studied in guinea-pig ventricular myocytes by means of whole-cell voltage clamp at 30 °C. 2. In external solution containing 144 mM Na(+) ([Formula: see text]) and...

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Hlavní autoři: Kockskämper, Jens, Erlenkamp, Simone, Glitsch, Helfried G
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2000
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269834/
https://ncbi.nlm.nih.gov/pubmed/10718738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.t01-2-00561.x
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