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Intracellular cyclic AMP inhibits native and recombinant volume-regulated chloride channels from mammalian heart

1. ClC-3 encodes a volume-regulated Cl(−) channel (I(Cl,vol)) in heart. We studied the regulation of native and recombinant cardiac I(Cl,vol) by intracellular cyclic AMP (cAMP(i)). 2. Symmetrical high Cl(−) concentrations were used to effectively separate outwardly rectifying I(Cl,vol) from other no...

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Detalhes bibliográficos
Main Authors: Nagasaki, Masaaki, Ye, Lingyu, Duan, Dayue, Horowitz, Burton, Hume, Joseph R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269833/
https://ncbi.nlm.nih.gov/pubmed/10718749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.00705.x
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