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Inhibition of nitric oxide synthase augments the positive inotropic effect of nitric oxide donors in the rat heart

1. In this investigation we studied the effects of nitric oxide on contractility and heart rate in normal saline-perfused rat hearts where shear stress-induced endothelial NO synthesis substantially contributes to total cardiac NO production. In addition, we sought to estimate the concentrations of...

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Autors principals: Müller-Strahl, Gerhard, Kottenberg, Karin, Zimmer, Heinz-Gerd, Noack, Eike, Kojda, Georg
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269760/
https://ncbi.nlm.nih.gov/pubmed/10639106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.00311.x
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