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Excitatory effect of P2X receptor activation on mesenteric afferent nerves in the anaesthetised rat

1. We examined the effects of P2X purinoceptor agonists and P2 purinoceptor antagonists on mesenteric afferent nerves supplying the jejunum in the pentobarbitone sodium-anaesthetised rat. 2. ATP (0.01–10 mg kg(−1), i.a.) and α,β-methylene-ATP (1–30 μg kg(−1), i.a.) each induced dose-dependent increa...

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Détails bibliographiques
Auteurs principaux: Kirkup, Anthony J, Booth, Charlotte E, Chessell, Iain P, Humphrey, Patrick P A, Grundy, David
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269593/
https://ncbi.nlm.nih.gov/pubmed/10523422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.00551.x
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