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Identification of amino acids within the P2X(2) receptor C-terminus that regulate desensitization

1. The ATP-activated P2X(2(a)) and P2X(2(b)) receptor splice variants, which differ only in their C-terminal sequences, desensitize at different rates. We used mutational analysis to investigate the involvement of the C-terminal region in receptor desensitization. Rat wild-type and mutant P2X(2) rec...

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Détails bibliographiques
Auteurs principaux: Smith, Fiona M, Humphrey, Patrick P A, Murrell-Lagnado, Ruth D
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269553/
https://ncbi.nlm.nih.gov/pubmed/10517803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.00091.x
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