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Crystal structure of chemically synthesized [N33A] stromal cell-derived factor 1α, a potent ligand for the HIV-1 “fusin” coreceptor

Stromal cell-derived factor-1α (SDF-1α ) is a member of the chemokine superfamily and functions as a growth factor and chemoattractant through activation of CXCR4/LESTR/Fusin, a G protein-coupled receptor. This receptor also functions as a coreceptor for T-tropic syncytium-inducing strains of HIV-1....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Dealwis, Chris, Fernandez, Elias J., Thompson, Darren A., Simon, Reyna J., Siani, Michael A., Lolis, Elias
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22694/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9618518/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.12.6941
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