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Gating current studies reveal both intra- and extracellular cation modulation of K(+) channel deactivation

1. The presence of permeant ions can modulate the rate of gating charge return in wild-type human heart K(+) (hKv1.5) channels. Here we employ gating current measurements in a non-conducting mutant, W472F, of the hKv1.5 channel to investigate how different cations can modulate charge return and whet...

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Detalhes bibliográficos
Main Authors: Wang, Zhuren, Zhang, Xue, Fedida, David
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269169/
https://ncbi.nlm.nih.gov/pubmed/10050001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.331ac.x
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