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Gating current studies reveal both intra- and extracellular cation modulation of K(+) channel deactivation
1. The presence of permeant ions can modulate the rate of gating charge return in wild-type human heart K(+) (hKv1.5) channels. Here we employ gating current measurements in a non-conducting mutant, W472F, of the hKv1.5 channel to investigate how different cations can modulate charge return and whet...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2269169/ https://ncbi.nlm.nih.gov/pubmed/10050001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.331ac.x |
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