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Dual allosteric modulation of pacemaker (f) channels by cAMP and voltage in rabbit SA node
1. A Monod-Whyman-Changeux (MWC) allosteric reaction model was used in the attempt to describe the dual activation of ‘pacemaker’ f-channel gating subunits by voltage hyperpolarization and cyclic nucleotides. Whole-channel kinetics were described by assuming that channels are composed of two identic...
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| Autore principale: | |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Science Inc
1999
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2269155/ https://ncbi.nlm.nih.gov/pubmed/10050004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.367ac.x |
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