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HOXB4 and retroviral vectors: adding fuel to the fire

The transcription factor homeobox B4 (HOXB4) is a promising agent capable of providing a growth advantage to genetically modified hematopoietic stem and progenitor cells (HSPCs). In this issue of the JCI, Zhang and colleagues overexpressed HOXB4 in HSPCs from large animals using retroviral vectors (...

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Autori principali: Larochelle, Andre, Dunbar, Cynthia E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268881/
https://ncbi.nlm.nih.gov/pubmed/18357348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35326
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