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HOXB4 and retroviral vectors: adding fuel to the fire

The transcription factor homeobox B4 (HOXB4) is a promising agent capable of providing a growth advantage to genetically modified hematopoietic stem and progenitor cells (HSPCs). In this issue of the JCI, Zhang and colleagues overexpressed HOXB4 in HSPCs from large animals using retroviral vectors (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Larochelle, Andre, Dunbar, Cynthia E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268881/
https://ncbi.nlm.nih.gov/pubmed/18357348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35326
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