Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma

The growth of normal cells is arrested when they come in contact with each other, a process known as contact inhibition. Contact inhibition is lost during tumorigenesis, resulting in uncontrolled cell growth. Here, we investigated the role of the tetraspanin transmembrane 4 superfamily member 5 (TM4...

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Hauptverfasser: Lee, Sin-Ae, Lee, Sung-Yul, Cho, Ik-Hyun, Oh, Min-A, Kang, Eun-Sil, Kim, Yong-Bae, Seo, Woo Duck, Choi, Suyong, Nam, Ju-Ock, Tamamori-Adachi, Mimi, Kitajima, Shigetaka, Ye, Sang-Kyu, Kim, Semi, Hwang, Yoon-Jin, Kim, In-San, Park, Ki Hun, Lee, Jung Weon
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268877/
https://ncbi.nlm.nih.gov/pubmed/18357344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33768
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