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Palmitate action to inhibit glycogen synthase and stimulate protein phosphatase 2A increases with risk factors for type 2 diabetes

Recent studies have suggested that abnormal regulation of protein phosphatase 2A (PP2A) is associated with Type 2 diabetes in rodent and human tissues. Results with cultured mouse myotubes support a mechanism for palmitate activation of PP2A, leading to activation of glycogen synthase kinase 3. Phos...

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Hlavní autoři: Mott, David M., Stone, Karen, Gessel, Mary C., Bunt, Joy C., Bogardus, Clifton
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268844/
https://ncbi.nlm.nih.gov/pubmed/18056794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00386.2007
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