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In vitro self-assembly of tailorable nanotubes from a simple protein building block

We demonstrate a method for generating discretely structured protein nanotubes from the simple ring-shaped building block, homohexameric Hcp1 from Pseudomonas aeruginosa. Our design exploited the observation that the crystal lattice of Hcp1 contains rings stacked in a repeating head-to-tail pattern....

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Detalhes bibliográficos
Main Authors: Ballister, Edward R., Lai, Angela H., Zuckermann, Ronald N., Cheng, Yifan, Mougous, Joseph D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268831/
https://ncbi.nlm.nih.gov/pubmed/18310321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712247105
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