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DNA binding shifts the redox potential of the transcription factor SoxR

Electrochemistry measurements on DNA-modified electrodes are used to probe the effects of binding to DNA on the redox potential of SoxR, a transcription factor that contains a [2Fe-2S] cluster and is activated through oxidation. A DNA-bound potential of +200 mV versus NHE (normal hydrogen electrode)...

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Autors principals: Gorodetsky, Alon A., Dietrich, Lars E. P., Lee, Paul E., Demple, Bruce, Newman, Dianne K., Barton, Jacqueline K.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268809/
https://ncbi.nlm.nih.gov/pubmed/18316718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800093105
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