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A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels

P-glycoprotein (MDR-1) is a well-known transporter that mediates efflux of chemotherapeutic agents from the intracellular milieu and thereby contributes to drug resistance. MDR-1 also is expressed by nonmalignant cells, including leukocytes, but physiologic functions for MDR-1 are poorly defined. Us...

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Detalhes bibliográficos
Main Authors: Randolph, Gwendalyn J., Beaulieu, Sylvie, Pope, Melissa, Sugawara, Isamu, Hoffman, Lloyd, Steinman, Ralph M., Muller, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22688/
https://ncbi.nlm.nih.gov/pubmed/9618515
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