Discovery of CD8(+) T cell epitopes in Chlamydia trachomatis infection through use of caged class I MHC tetramers

Class I MHC tetramers allow direct phenotypic identification of CD8(+) T cell populations, but their production remains laborious. A peptide exchange strategy that employs class I MHC products loaded with conditional ligands (caged MHC molecules) provides a fast and straightforward method to obtain...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Grotenbreg, Gijsbert M., Roan, Nadia R., Guillen, Eduardo, Meijers, Rob, Wang, Jia-huai, Bell, George W., Starnbach, Michael N., Ploegh, Hidde L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2008
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268777/
https://ncbi.nlm.nih.gov/pubmed/18245382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711504105
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