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Dissection of the Osteogenic Effects of Laminin-332 Utilizing Specific LG Domains: LG3 Induces Osteogenic Differentiation, but not Mineralization

The overall mechanisms governing the role of laminins during osteogenic differentiation of human mesenchymal stem cells (hMSC) are poorly understood. We previously reported that laminin-332 induces an osteogenic phenotype in hMSC and does so through a focal adhesion kinase (FAK) and extracellular si...

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Detalhes bibliográficos
Main Authors: Klees, Robert F., Salasznyk, Roman M., Ward, Donald F., Crone, Donna E., Williams, William A., Harris, Mark P., Boskey, Adele, Quaranta, Vito, Plopper, George E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268764/
https://ncbi.nlm.nih.gov/pubmed/18206871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.12.007
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