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Evaluation of two methods for computational HLA haplotypes inference using a real dataset

BACKGROUND: HLA haplotype analysis has been used in population genetics and in the investigation of disease-susceptibility locus, due to its high polymorphism. Several methods for inferring haplotype genotypic data have been proposed, but it is unclear how accurate each of the methods is or which me...

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Bibliografske podrobnosti
Main Authors: Bettencourt, Bruno F, Santos, Margarida R, Fialho, Raquel N, Couto, Ana R, Peixoto, Maria J, Pinheiro, João P, Spínola, Hélder, Mora, Marian G, Santos, Cristina, Brehm, António, Bruges-Armas, Jácome
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268655/
https://ncbi.nlm.nih.gov/pubmed/18230173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-68
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