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Ultrasonic vocalization impairment of Foxp2 (R552H) knockin mice related to speech-language disorder and abnormality of Purkinje cells

Previous studies have demonstrated that mutation in the forkhead domain of the forkhead box P2 (FOXP2) protein (R553H) causes speech-language disorders. To further analyze FOXP2 function in speech learning, we generated a knockin (KI) mouse for Foxp2 (R552H) [Foxp2 (R552H)-KI], corresponding to the...

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Bibliographische Detailangaben
Hauptverfasser: Fujita, Eriko, Tanabe, Yuko, Shiota, Akira, Ueda, Masatsugu, Suwa, Kiyotaka, Momoi, Mariko Y., Momoi, Takashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268594/
https://ncbi.nlm.nih.gov/pubmed/18287060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712298105
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