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BH3-only protein Puma contributes to death of antigen-specific T cells during shutdown of an immune response to acute viral infection

During acute T cell immune responses to viral infection, antigen-specific T cells first proliferate and differentiate into effector cells, but after pathogen clearance most are deleted by apoptosis. The developmentally programmed death of antigen-specific T cells during shutdown of a T cell response...

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Detalhes bibliográficos
Main Authors: Fischer, Silke F., Belz, Gabrielle T., Strasser, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268580/
https://ncbi.nlm.nih.gov/pubmed/18287039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706913105
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