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Gene Overexpression/Suppression Analysis of Candidate Virulence Factors of Candida albicans

We developed a conditional overexpression/suppression genetic strategy in Candida albicans to enable simultaneous testing of gain or loss of function in order to identify new virulence factors. The strategy involved insertion of a strong, tetracycline-regulated promoter in front of the gene of inter...

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Detalhes bibliográficos
Main Authors: Fu, Yue, Luo, Guanpingsheng, Spellberg, Brad J., Edwards, John E., Ibrahim, Ashraf S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268510/
https://ncbi.nlm.nih.gov/pubmed/18178776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00445-07
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