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Direct visualization of antigen-specific T cells: HTLV-1 Tax11–19- specific CD8(+) T cells are activated in peripheral blood and accumulate in cerebrospinal fluid from HAM/TSP patients

Human T lymphotropic virus type 1 (HTLV-1) -associated myelopathy/tropic spastic paraparesis is a demyelinating inflammatory neurologic disease associated with HTLV-1 infection. HTLV-1 Tax11–19-specific cytotoxic T cells have been isolated from HLA-A2-positive patients. We have used a peptide-loaded...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Greten, Tim F., Slansky, Jill E., Kubota, Ryuji, Soldan, Samantha S., Jaffee, Elizabeth M., Leist, Thomas P., Pardoll, Drew M., Jacobson, Steven, Schneck, Jonathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22685/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9636190/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.13.7568
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