Short-Lived Infected Cells Support Virus Replication in Sooty Mangabeys Naturally Infected with Simian Immunodeficiency Virus: Implications for AIDS Pathogenesis

Sooty mangabeys (SMs) naturally infected with simian immunodeficiency virus (SIV) do not develop AIDS despite high levels of virus replication. At present, the mechanisms underlying this disease resistance are poorly understood. Here we tested the hypothesis that SIV-infected SMs avoid immunodeficie...

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Main Authors: Gordon, Shari N., Dunham, Richard M., Engram, Jessica C., Estes, Jacob, Wang, Zichun, Klatt, Nichole R., Paiardini, Mirko, Pandrea, Ivona V., Apetrei, Cristian, Sodora, Donald L., Lee, Ha Youn, Haase, Ashley T., Miller, Michael D., Kaur, Amitinder, Staprans, Silvija I., Perelson, Alan S., Feinberg, Mark B., Silvestri, Guido
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268472/
https://ncbi.nlm.nih.gov/pubmed/18216113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02408-07
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