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Functional Dissection of the NuA4 Histone Acetyltransferase Reveals Its Role as a Genetic Hub and that Eaf1 Is Essential for Complex Integrity

The Saccharomyces cerevisiae NuA4 histone acetyltransferase complex catalyzes the acetylation of histone H4 and the histone variant Htz1 to regulate key cellular events, including transcription, DNA repair, and faithful chromosome segregation. To further investigate the cellular processes impacted b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mitchell, Leslie, Lambert, Jean-Philippe, Gerdes, Maria, Al-Madhoun, Ashraf S., Skerjanc, Ilona S., Figeys, Daniel, Baetz, Kristin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268438/
https://ncbi.nlm.nih.gov/pubmed/18212056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01653-07
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