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Trypanosoma brucei RNA Editing: Coupled Cycles of U Deletion Reveal Processive Activity of the Editing Complex

RNA editing in Trypanosoma brucei is posttranscriptional uridylate removal/addition, generally at vast numbers of pre-mRNA sites, but to date, only single editing cycles have been examined in vitro. We here demonstrate achieving sequential cycles of U deletion in vitro, with editing products confirm...

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Main Authors: Alatortsev, Vadim S., Cruz-Reyes, Jorge, Zhelonkina, Alevtina G., Sollner-Webb, Barbara
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268434/
https://ncbi.nlm.nih.gov/pubmed/18227152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01886-07
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