Inducible Expression of Chimeric EWS/ETS Proteins Confers Ewing's Family Tumor-Like Phenotypes to Human Mesenchymal Progenitor Cells

Ewing's family tumor (EFT) is a rare pediatric tumor of unclear origin that occurs in bone and soft tissue. Specific chromosomal translocations found in EFT cause EWS to fuse to a subset of ets transcription factor genes (ETS), generating chimeric EWS/ETS proteins. These proteins are believed t...

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Main Authors: Miyagawa, Yoshitaka, Okita, Hajime, Nakaijima, Hideki, Horiuchi, Yasuomi, Sato, Ban, Taguchi, Tomoko, Toyoda, Masashi, Katagiri, Yohko U., Fujimoto, Junichiro, Hata, Jun-ichi, Umezawa, Akihiro, Kiyokawa, Nobutaka
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268432/
https://ncbi.nlm.nih.gov/pubmed/18212050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00740-07
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