TAZ Promotes Cell Proliferation and Epithelial-Mesenchymal Transition and Is Inhibited by the Hippo Pathway

TAZ is a WW domain containing a transcription coactivator that modulates mesenchymal differentiation and development of multiple organs. In this study, we show that TAZ is phosphorylated by the Lats tumor suppressor kinase, a key component of the Hippo pathway, whose alterations result in organ and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lei, Qun-Ying, Zhang, Heng, Zhao, Bin, Zha, Zheng-Yu, Bai, Feng, Pei, Xin-Hai, Zhao, Shimin, Xiong, Yue, Guan, Kun-Liang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2008
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268418/
https://ncbi.nlm.nih.gov/pubmed/18227151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01874-07
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