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A multimetric approach to analysis of genome-wide association by single markers and composite likelihood
Two case/control studies with different phenotypes, marker densities, and microarrays were examined for the most significant single markers in defined regions. They show a pronounced bias toward exaggerated significance that increases with the number of observed markers and would increase further wi...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268181/ https://ncbi.nlm.nih.gov/pubmed/18268331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711903105 |
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