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A multimetric approach to analysis of genome-wide association by single markers and composite likelihood

Two case/control studies with different phenotypes, marker densities, and microarrays were examined for the most significant single markers in defined regions. They show a pronounced bias toward exaggerated significance that increases with the number of observed markers and would increase further wi...

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Main Authors: Gibson, Jane, Tapper, William, Cox, David, Zhang, Weihua, Pfeufer, Arne, Gieger, Christian, Wichmann, H.-Erich, Kääb, Stefan, Collins, Andrew R., Meitinger, Thomas, Morton, Newton
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268181/
https://ncbi.nlm.nih.gov/pubmed/18268331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711903105
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